diff --git a/constraints.txt b/constraints.txt
new file mode 100644
index 0000000000..697aca1388
--- /dev/null
+++ b/constraints.txt
@@ -0,0 +1,3 @@
+# Workaround for https://github.com/pypa/setuptools/issues/4519.
+# Applies only for Django tests.
+setuptools<72.0.0
diff --git a/tox.ini b/tox.ini
index 3ab1bae529..eae6f054b5 100644
--- a/tox.ini
+++ b/tox.ini
@@ -648,6 +648,7 @@ setenv =
     OBJC_DISABLE_INITIALIZE_FORK_SAFETY=YES
     COVERAGE_FILE=.coverage-{envname}
     django: DJANGO_SETTINGS_MODULE=tests.integrations.django.myapp.settings
+    py3.12-django: PIP_CONSTRAINT=constraints.txt
 
     common: TESTPATH=tests
     gevent: TESTPATH=tests